Ε-polylysine and its hydrochloride are widely used

Food business network information ε- polylysine by the body is an essential amino acid - lysine amide linkage formed by a homopolymer α- and ε- amino hydroxy, amino acids forming a degree of polymerization of between 25 and 35 Linear polymer. It is a natural product with antiseptic function purified from the culture solution of amylase-controlled Streptomyces sp. by ion exchange resin. Lysine is one of the eight essential amino acids in the human body. ε-polylysine and its hydrochloride will decompose into lysine after entering the digestive tract of the human body, which is digested and absorbed by the human body. Therefore, ε-polylysine and Its hydrochloride is not only a nutritional biopreservative, but also a source of lysine.

Ε-polylysine hydrochloride can be decomposed into lysine in the human body, and lysine is one of the eight essential amino acids required by the world, and it is also a fortified amino acid that is allowed to be added to foods in various countries of the world. Therefore, ε-polylysine hydrochloride is a nutritive bacteriostatic agent with high safety and an LD50 of 5 g/kg.

According to data provided by a Japanese manufacturer of ε-polylysine, ε-polylysine is a homopolymer composed of 30 L-lysines linked by an amide bond between a carboxyl group and an ε-amino group, and 30 homopolymers. The relative molecular weight of the material was 4,700. Experiments with radioisotope-labeled ε-polylysine in mice showed that 94% of ε-polylysine was excreted and not deposited in tissues and organs, and a small amount of ε-polylysine was Degraded to lysine or 4-6 polymers. Lysine is an essential amino acid in the human body and can be used by the human body to synthesize proteins of human tissues or to enter the next step of metabolism. The manufacturer also conducted subchronic and chronic toxicology and carcinogenesis experiments, and no significant histopathological changes were observed. To this end, on July 10, 2003, the manufacturer submitted an application to the US Food and Drug Administration requesting the US Food and Drug Administration to identify its product ε-polylysine as a GRAS (Generally Recognized As Safe) product, 2004 On January 16, the US Food and Drug Administration replied to the application, approving ε-polylysine as a GRAS product, and numbering it as a safe food GRAS (Announcement No. GRN000135), a chemical summary of ε-polylysine The service registration code CAS is 28211-04-03. According to the relevant US legal requirements, the US Food and Drug Administration's open letter, along with the application information provided by the manufacturer, is subject to public inquiry, and all contents can be found and copied on the homepage of the US Food and Drug Administration's Security Office.

Japan, South Korea and the United States have successively approved ε-polylysine as a food preservative for a wide range of applications. In April 2014, China approved ε-polylysine and its hydrochloride as new food additive varieties. Zhejiang Xinyinxiang Bioengineering Co., Ltd. is the standard drafting unit of ε-polylysine hydrochloride. In addition to its application in the field of food processing, ε-polylysine is also used in the catering industry, such as for preservative preservation of rice.

Ε-polylysine or its hydrochloride is used as a food preservative. At present, ε-polylysine or its hydrochloride biocellulose antibacterial casing, ε-polylysine/PVA composite antibacterial packaging film, ε-polylysine antibacterial hand soap, ε-polylysine have been developed. A variety of products such as acid antibacterial cotton cloth, ε-polylysine antibacterial water-absorbing sanitary material, etc., have broad application prospects in many fields.

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