The effects and effects of Alisma
1, sexual taste: Gan, cold.
1 "The Classic": Sweet, cold.
2 "Do not record": salty, non-toxic.
9 "Theory of Medicine": bitter taste.
4 "Medical Kaiyuan": flat and sweet.
5 "Materia Medica Mang": Gan acid, cold air.
2, go by: kidney, bladder by.
1 "Dessert Materia Medica": start the sun, Shaoyin.
2 "Ben Cao Yan Yi Supplements": Into the sun, Shao Yin Jing.
3 "Lei Gong gun pharmaceutical solution": into the bladder, kidney, triple burner, small intestine four classics.
4 "Materia Medica": enter the kidney and spleen.
3, effectiveness: water, moisture, heat. Treatment of urine is unfavorable, edema is full, vomiting, diarrhea, phlegm, beriberi, gonorrhea, hematuria.
1 "The Classic": The main wind is cold and wet, milk is difficult, eliminate water, raise five internal organs, benefit strength, fatness.
2 "Do not record": make up for five labor, in addition to the five internal organs full, from the yin, stop bleeding essence, Diabetes, Lin Lek, by the bladder, San Jiao stopped.
3 "Medicinal Theory": The main kidney essence is self-eating, rule Wuling, Li bladder heat, straight through the waterway.
4 "Japan Hanako Materia Medica": the rule five workers and seven injuries, the main head spin, ears voicing, muscles contracture, pass the small intestine, only left Lek, hematuria. '
5 "Medical Kaiyuan": rule urine pouring Lek, go to the underworld sweat. Go old water, raise new water, facilitate urination, eliminate edema, and stop bleeding.
6 Li Yu: To leave the dirt in the skull, under the heart of water.
7 "Outline": hot and humid, phlegm, vomiting, diarrhea, phlegm, athlete's foot. [7]
4, usage and consumption: oral administration, Jiantang, 2-4 money; or into the pill, scattered.
5, drug contraindications: Kidney deficiency slippery Jifu.
1 "Ben Cao Zai Zhuan": Fear of the sea, Wen Hao.
2 "Do not record": flat cloud, more patients eye.
5 "Introduction to medicine": Where the shower, thirst, edema, caused by kidney deficiency, not available.
4 "Ben Cao Jing Shu": The patient is not wet and dripping, and lack of kidney qi, kidney qi lack of absolute, self-efficacy of yang decline, kidney qi is not solid slippery, eye pain, Deficiency cold for vent Hou Hou, method of salty avoid.
6, common prescriptions:
1 "supreme pathogenesis insurance set" Atractylodesis scattered: governance swelling edema: Atractylodes, Alisma two and a half. On the go-between, decocting three money, soup soup, or pills can also serve thirty pills.
2 "Golden Chamber" Azolla soup: There is a drink under the control of the heart, and its people are bitter and emaciated: Alisma five-two, Atractylodes two two. On the two flavors, two liters of water, boil one liter, and sub-warm clothes.
3 "Outline" Three white powder: cure cholera, urination, dizziness cited drinking: Alisma, Atractylodes, white peony all three money. Water - wolfberry, ginger five, wick 10 stems, fry 8 minutes, warm clothes.
4 "women's good recipe" Alisma powder: rule pregnancy bloated over all over, breathlessness, urgency, loose stools, urine red astringent: Alisma, Morus alba (fried), betel nut, red peony five points. Ginger decoction.
5 "Qian Jin Fang": cure hot and humid Huang Qi, face the body of yellow: Yin Chen, Alisma, one or two, talc three money. Shuijianbi.
6 "Surgical authentic": governance cold wet athlete's foot, there are cold and heat: Alisma, papaya, Bupleurum, Atractylodes, Poria, wood pass, each five money. Shuijianbi.
7 "Proclaiming the Essays" Alias ​​scattered: rule children's é½è›¤, 膈 壅 壅 壅 涎 hot, 涎 : tide: a diarrhea, è‰ ( ( (all) twenty-one, yellow gelatin (a large palm, ç‚™ 焦 Jiao) . On the go-between. Each serving a money, warm rice soup tune down, day two service, healed again.
8 "Su Wen": The rule of wine style, the body heat to relax idle, sweat like a bath, evil wind less gas: Alisma, surgery is very, and the title five points. Together, with three fingers, after dinner.
9 "San Ji Zong Lu" Alisma San: cure wind and sweat, evil wind shudder: Alisma, wind (peel), oysters (forging red), Atractylodes (rice Baptist, peeled, fried) each one or two , Gui (to rent leather) three points. On the five flavors, Milo is finely scattered. Every serving of two money, warm porridge drink down, not time.
10 "experience side": governance kidney wind sore: Alisma, acacia, boiled water, drying to the end, refining honey for the pill, such as large Tongzi. Hollow, take 15 pills under warm wine to 20 pills. [7]
7, each discussion:
1 "Ben Cao Yanyi": Alisma, its power is especially longer than line water. The "Ben" has also introduced the flat cloud, taking more patient's eye astringent, sincerely to go to the water. Today people stop draining sperm and do not dare to use it.
2 "Medicine's Retrospective Collection": Zhang Zhongjing Bawei Pills with Alisma, is the use of Zawei Pills with Alias ​​without him, to cover its diarrhea kidney evil, raising five internal organs, Qi strength, from the yin, tonic loss The power.
3 "Materia Medica Mongol": Alisma, although many services but dizzy, brutal clothing can also be the eyesight, its right? Cover diarrhea water, to keep dirt, so the eyesight; small convenience, kidney qi deficiency, so faint. Both must know.
4 "Outline": Alisma, flat, sweet and light, light energy leakage, thin odor, so the water leaked. Shennongshuliezai rushed to the top grade, Fuyun took a light body, and looked at the light. Tao and Su all believed that they were stupid and suspicious. Alisma diarrhea kidneys, Jiufu and can not, but also have this God Gongye, the other is known.
5 "Ben Cao Hui Yan": Fang Longtan cloud, Alisma has the power of Gu Shen Zhi Shui, and then there are different people with the pig.
6 "Bencao Tong Xuan": cover phase fire anger and left behind, get diarrhea, clear and self-hidden, qi deficiency subsidence and smooth slippery, get cassia diarrhea down the fine and more smooth.
7 "Drugification of justice": Where is diarrhea, small water will be a short number, in order to (Azeri) clear and moist lungs, pass through the water, under the bladder, attending water diarrhea, diarrhea, so that the stool is real, then the temper from Jian also. Because of the ability to benefit the waterway and let the evil water go, the true water is raised, so that thirst can stop.
8 "Materia Medica Justice": Alisma, the most good penetration of waterways, special access to urine.
Pharmacological effects
1. Hypolipidemic effect: Lipid-soluble part of Alisma orientale has significant cholesterol-lowering and anti-atherosclerotic effects on rabbits with experimental hypercholesterolemia, from which Alisma alcohol A, B and Alisma are isolated. The acetates of alcohols A, B and C, in addition to alcroseol B, have significant cholesterol-lowering effects. Adding 0.1% to the diet of experimental hyperlipidemic rats can reduce blood cholesterol by more than 50%, of which the most effective is Azaleas A-24-acetate. Ethanol extracts of Alisma orientalis and ethyl acetate extracts of ethanol extracts have lipid-lowering effects on experimental hypercholesterolemic rabbits and rats. The ethyl acetate extract and its residue insoluble in acetic acid-water are the most potent. Ethyl acetate extract was taken orally at 1 g/kg daily, and it also showed significant cholesterol-lowering effect on normal rats fed normal diets. Equipotential mark method proved that Alisma alcohol A had the ability to inhibit the esterification of cholesterol in mouse small intestine, and could reduce the absorption rate of cholesterol in rat small intestine by 34%, but did not affect the absorption of linoleic acid.
2. Protective effects on the liver: Alisma alcohol A acetate, Alisanilide B acetate and Alisanilide C acetate can protect liver of mice poisoned by carbon tetrachloride, in which Alisma alcohol C Acetate works best.
3. Effect on the cardiovascular system: Alisma extract is given intravenously to dogs and rabbits and has a mild antihypertensive effect, which lasts for about 30 minutes. Alismadiol has a mild antihypertensive effect on various experimental animals, and its antihypertensive effect does not significantly affect plasma renin and ACE activity or aldosterone levels. Alisma alcohol extract has a slow relaxing effect on adrenergic induced aortic contraction of rabbits in vitro. Alismolol inhibits the contraction of rabbit aortic strips caused by angiotensin and its contraction is dose-dependent. Alismatogenol with isolated cardiac perfusion techniques can reduce cardiac output and heart rate as well as left ventricular pressure, but can increase coronary flow.
4. Diuresis: Diuresis experiments were performed with saline-loaded mice or rats. Subcutaneous injections of acneol A acetate 100 mg/kg subcutaneously increased the secretion of K+ in urine, but oral administration of the same dose was ineffective. When rats were orally administered with a dose of 30 mg/kg of acethyl acetate A or aciniol B, the amount of Na+ was significantly increased, compared with the control group P<0.05 and P<0.01.
Toxicological toxicity
Alisma, the whole plant is poisonous, and underground tubers are more toxic. Stems and leaves contain toxic sap, and the skin of the livestock can be itchy, red, and foamy. After eating, it can cause abdominal pain, diarrhea and other symptoms. It can also cause paralysis. A new substance, TLD50, was extracted from mice with intravenous injection of Alisma of 780 mg/kg and intraperitoneal injection of 1270 mg/kg. [8] Toxicity T (1.1.1.1) has a median lethal dose of 780 mg/kg for intravenous injection in mice, 1270 mg/kg for intraperitoneal injection and 4000 mg/kg for oral administration. At the concentration of 0.1% and 1% in the diet, two and a half months after feeding, there was no significant change in body weight, visceral weight, and liver fat volume. Alisma contains irritant substances taken orally that can cause gastroenteritis, stick to the skin to cause foaming, and its leaves can act as a skin redness agent. Sheep eat this plant harmless, and cattle can cause poisoning, showing hematuria. The median lethal doses of intravenous and intraperitoneal injections of the methanol extract of Alisma orientalis were 0.98 and 1.27 g/kg, respectively. Oral 4.0g/kg. The rats were fed 1% of the feed for 75 days without significant toxicity. Alisma alcohol infusion 100mg/kg mouse intraperitoneal injection, observed 72 hours, no one died. A total of 1g and 2g/kg of Alisma extract powder (20 and 40 times of the corresponding clinical dosage) was fed to the rats in the feed for a total of 3 months. The animals were generally in good health, with increased body weight, serum glutamic-pyruvic transaminase activity, and hemoglobin There was no significant difference between the volume and the control group, but pathological examination revealed that the hepatocytes and renal proximal tubule cells had different degrees of edema and degeneration. The administration group was more obvious than the control group. The high-dose group was significantly more than the small-dose group. May be related to administration, but no significant changes in heart tissue.
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