Genetic technology advances precision medical future or becomes a reality

Precision medicine is not a vocabulary that Americans just proposed this year. It was first proposed by the National Research Council in 2011. Previously, people have proposed the "4P medical model", namely, prediction, prevention, participation, and personalized medicine , and precision has become the fifth P.

It combines digital healthcare with big data, sometimes referred to as personalized medicine. Although the difference between the two is negligible in some areas, precision medicine emphasizes molecular level information. The starting point is the individual's genetic makeup, environment, lifestyle, and other specific information that not only predicts the individual's future health, but also demonstrates the individual's response to treatment options.

In the mid-1980s, geneticist Roden came to Vanderbilt University in the United States. He has been thinking about the question: Why does the patient's body respond differently to medication? How to use personalized information to make the best medical decisions?

For about 30 years, Roden and his team have been studying how to combine patient genetic information with electronic medical records to help patients predict the effects of medications. However, the most critical of these is genetics. Roden said that personalized medicine is not just your genetic code, it is about all factors, giving you a unique health experience.

Earlier this year, US President Barack Obama let Roden's question melt into a huge budget plan. In his State of the Union address, he said, "I hope that this country that has eliminated polio and mapped out human genetic maps will lead a new era of medicine and give correct treatment at the right time." "Tonight, I want to launch a The new 'Precision Medical Initiative' allows us to move toward the goal of curing diseases such as cancer and diabetes, as well as the individualized information we need to keep ourselves and our family members healthy."

This sounds like a historic moment. In a famous speech in the 1960s, former US President Kennedy once said: We decided to go to the moon. Not because they are simple, but because they are difficult. According to Mary Beckler, director of the Huntsman Cancer Institute at the University of Utah, the important component of the precision medical project is the sequencing of a lunar probe that leads people to the moon. Beckler believes that achieving medical breakthroughs requires visionary leadership, courage and willingness to break the limits of human knowledge. For the prevention and early detection of certain cancers, there are actually ready-made tools in our medical kits. What are the reasons for stopping?

Obama's vision of "two steps"

One day in April 1953, Crick and Watson published a paper on which they discovered the double helix structure of DNA based on the work of their predecessors, and for the first time spy on how the living body inherits and stores biological information. Today, more than sixty years later, their discovery is having a revolutionary impact.

Imagine a man who was diagnosed with a benign tumor, compared to a chemotherapy that would cost thousands of dollars and would be difficult to talk about, he would get an affordable treatment that would save his life. Today, only a small bottle of mother's blood is needed, and DNA sequencing technology can help screen for diseases such as Down's syndrome and other health conditions in the fetus.

Behind it is the deconstruction of the genetic world and the "attack" of precision medicine. In fact, precision medicine is not a vocabulary that Americans just proposed this year. It was first proposed by the National Research Council in 2011. Previously, people have proposed the "4P medical model", namely, prediction, prevention, participation, and personalized medicine, and precision has become the fifth P.

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