Endometrial regeneration brings "recycled baby" to infertile patients

Release date: 2017-05-24

Xinhua News Agency, Nanjing, May 22 (Reporter Zheng Shengzhu, Dong Ruifeng) Severe uterine adhesions caused by severe endometrial damage have been considered to be the terminal cause of infertility. The reporter learned from the Center for Regenerative Medicine of the Institute of Genetic Development of the Chinese Academy of Sciences that the team of researcher Dai Jianwu and the endometrial regeneration developed by Nanjing Drum Tower Hospital have made important breakthroughs since the clinical research in 2013. 13 patients with intrauterine adhesions have passed. This technology gave birth to “recycled baby”.

"After the endometrial injury, there will be obvious scarring, insufficient blood supply, resulting in the implantation of fertilized eggs, just as the land becomes a cement land and can not grow out of plants." According to the vice president of Nanjing Gulou Hospital, maternity Director Hu Yali said that with the increase of intrauterine operation, the incidence of intrauterine adhesions has increased, which has become an important cause of secondary infertility in women. The latest statistics show that the number of infertile people in China has exceeded 50 million, and infertility patients due to intrauterine adhesions account for a large part.

Ms. Zhou from Nanjing had induced labor due to a heart attack in the fetus in 2012, which led to the occurrence of intrauterine adhesions and infertility. After that, I had a hysteroscopic adhesion separation, and the effect was not very good. In 2014, she had a retrograde pregnancy and childbirth after undergoing endometrial regeneration in the Drum Tower Hospital. Her child has now been more than 8 months old. "Children more than 70 centimeters, more than 19 pounds, all indicators are normal." Ms. Zhang said.

"The role of stem cells is to secrete a lot of nutrients, just like the organic matter used for soil improvement. After the stem cells are placed on the scaffold material, they can attract the blood vessels to the scaffold, and then the cells are pulled to form a new inner membrane, or let the inner Membrane thickening." According to Dai Jianwu, the current hysteroscopic adhesion separation is a classic method for the treatment of intrauterine adhesions, but the prevention of adhesion recurrence is not good. The innovation of endometrial regeneration technology is to use the scaffold material to help stem cells colonize and differentiate, thereby realizing the regeneration of blood vessels and tissues, repairing scarred endometrium, and providing implantation and development environment for fertilized eggs.

According to reports, the technology has been innovated in many details, and obtained a number of patents. Therefore, the technology belongs to the field of medical devices based on biological materials and stem cells. In the future, medical technology companies can transform this scientific and technological achievements, and it is expected to be industrialized after three or four years.

Source: Sina Technology

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