Lithospermum clinical treatment
Clinical treatment
1. Treatment of acute and chronic hepatitis: The dry powder of Lithospermum extracted from Lithospermum erythrorhizon was used as a smelt, and sodium hydroxide solution was used as a solvent to prepare 0.2% Lithospermum injection. Intramuscular injection, 1-2 times daily, 2ml each time. Observed 13 cases of jaundice-type infectious hepatitis, all cured; 159 cases of acute non-yellox type contagious hepatitis, cured 139 cases, markedly improved in 6 cases, improved in 12 cases; chronic hepatitis in 113 cases, cured in 84 cases, markedly improved in 14 cases, improved In 2 cases, 13 cases were invalid. In addition, 4 cases of liver cirrhosis have also achieved certain efficacy.
2. Treatment of pulmonary tuberculosis with thrombocytopenic purpura: 1 case was reported, the effect of general Western and Chinese comprehensive treatment is not significant, after switching to a large number of lithospermum effect. On the first day, two were used. After the serving, the nasal discharge was reduced. On the second day, two were added. The nasal discharge was completely stopped. Five continuous doses were used, and the platelet count was increased to 170,000/mm3. The systemic purpura disappeared and the condition turned to danger. There was diarrhea after taking the drug, but the patient did not feel uncomfortable.
3. Treatment of malignant hydatidiform mole complicated by uterine chorionic epithelial cancer: One case was reported. X-ray findings after the operation revealed metastatic lesions in the lungs. After one month of observation, the metastatic lesions gradually expanded and clinical symptoms became worse. Lithospermum root 1 two, daily decoction 1, 10 days for a course of treatment. After four courses of treatment, clinical symptoms were greatly reduced, and most of the X-ray lesions disappeared. After continuing to take shikonin for 1 month, all clinical symptoms disappeared and urine pregnancy was negative.
4. Treatment of infantile dermatitis, vulva eczema, vaginitis and cervicitis: Use 2%, 10%, 20%, 40% lithospermum oil infusion, or lithosperm ethyl ether extract formulated as a 1% vegetable oil preparation for local application.
4.1. 100 cases of infants with buttocks dermatitis were treated, and there was no case of erosion after treatment.
4.2. Women with urogenital genital warts often suffer from eczema, erosions, ulcers, and various causes of vaginal discharge due to frequent urine leaks. After applying lavender oil for 3-5 days, it can be effective. He had treated 28 cases and healed 24 cases.
4.3. For vaginitis, generally cured 4-6 days after application, and the recurrence rate is very low. 234 cases were treated and the cure rate was 77.7%.
4.4. If cervicitis is associated with pelvic inflammatory disease or severe erosion, congestion, and purulent secretions, can easily cause bleeding, infection and acute exacerbation of pelvic inflammatory disease, can be applied lithospermum oil. According to the severity of illness, for 1-3 consecutive weeks, congestion and purulent secretions can disappear until it is cured. 182 cases were treated and 96 cases were cured. The higher the concentration of lithospermum oil, the better the effect, and increasing the concentration without any side effects. Lithospermum oil seems to have no antibacterial effect, and its principle of clinical efficacy needs further study.
5. Treatment of youth with flat warts and psoriasis: Lithospermum erythrorhizon extract made with 0.1% injection, intramuscular injection of 2ml each time; a small number of patients with psoriasis with intravenous 0.05% Lithospermum injection, each time 10ml. All once daily. Young flat warts in 23 cases, after treatment 7-10 times, cured (conscious symptoms disappeared, all or most of the rash subsided) 10 cases, effect (symptoms relieved, skin rash significantly smaller or flattened or pale spots, thinning scales ) 10 cases, invalid (no more than 10 injections did not improve the rash) in 3 cases. Psoriasis intramuscular injection in 29 cases, after 10-20 treatment, 5 cases were cured, 15 cases were markedly effective, 9 cases were ineffective; 7 cases were intravenously treated, 3 cases were cured after 10 times, 1 case was marked, 3 cases were invalid . Initial observations showed that the effect of the flat warts was indeed, the course of treatment was significantly shortened, and the recurrence rate was low. Psoriasis is better for progressive lesions. The disadvantage is injection of local pain. Another once used Lithospermum root 20g plus dimethyl sulfoxide 100ml, soaked 3-4 days after the liquid to apply local, 1-2 times a day; treatment of flat warts more than 20 cases, generally see the flat wart off after 1-2 weeks or calm.
6. Treatment of pityriasis rosea: Use 0.5-1 osmium (2-5 money for children), decoct a daily dose, 10 days for a course of treatment. After a certain interval can continue to take several courses. In 70 cases, 37 cases were cured, 25 cases were improved, and 8 cases were ineffective. The average medication for 9 days, up to no more than 2 months.
7. Regarding the Prevention of Measles: Purple Lithospermum has been widely used in the prevention of measles, but the usage is not the same and the results are very inconsistent.
8. Lithospermum root decoction, pills and compound Lithospermum root decoction (Erythrorhizopsis root, Atractylodes macrocephala, woody incense) were administered orally.
The dosage of the main medicine Lithospermum root is:
8.1. From 6 months to 1 year 6 points, from 1 year old to 2 years old, 8 points, and every 2 years old or more with 1 year old increase by 2 points. The above are all on the 1st, 3 servings, and even 4 days. A total of 968 scattered children with a history of measles exposure from the age of 6 months to 8 years were observed, 94 of whom were 9.72%. There are no major differences in the effects of the three formulations. It is believed that the protection rate of comfrey on preventing measles is 90.2%.
8.2. Use 33% Lithospermum root syrup, 10 ml every 6 months to 1 year old, 20 ml 2-3 years old, and 30 ml 4-6 years old. Take 2 times every other day for a total of 3 days, 6 times. Once the suspicious children were scattered in 110 rural villages, this syrup was administered for prevention. As a result, there were 3 cases of rash, and the protection protection rate was 97.3%. In addition, 685 of the susceptible children in rural areas were observed for preventive observation using the above method. As a result, the incidence rate after treatment was gradually decreased from 11.3% before administration to 1.1%. Most of the children who had not had measles were immunized after taking the medicine. For patients with latent period or prodromal period, they all shortened the period after taking the medicine, and at the same time, the measles were issued quickly.
8.3. Lithospermum root uses 1.5 yuan for the first year of age, 2 dollars for 2-8 years old, 2.5 dollars for 9-12 years old, add 100ml of water, boil for 3 minutes, and serve in 1 day. Take only 1 day. A total of 1480 cases of scattered children were observed, of which 135O cases did not show an eruption during an average of 2 weeks, and the other 130 cases had a milder clinical symptoms.
8.4. Use 1:1 comfrey, turfgrass, and comfrey root syrup; 1 ml each within 1 year, 2 ml in 2-3 years, and 3 ml in 4-6 years, all served on the same day 3 times for 4 days. A total of 1607 children were observed in cities scattered from 4 months to 16 years old. The results showed that the effect of comfrey root was the best, the incidence rate was 8.58%; purple velvet grass was poor, and the incidence string was 15%; purple turf had no obvious preventive effect. White blood cell decrease.
8.5. Use 33% Lithospermum root solution, 15ml each time, 2 times a day, and 2 days a week. During the epidemic, 133 children aged 2-6 years who had not had measles were taken preventive medication at 6 nurseries. Results The incidence of medication after 112 patients, the incidence rate of 84.2%, of which 13 were complicated by pneumonia.
8.6. Use 2 parts of Lithospermum root and 1 part of licorice to make powder. 0.6g over 6 months, 1g over 2 years old, 1.5g over 4 years old, 2.5g over 5-7 years old. All served 3 times a day, even for 3 days. A total of 471 susceptible children (258 in the medication group and 213 in the control group) who were 6 months to 7 years old during the epidemic season were observed. The incidence of the medication group was eventually reduced, and the latent period, prodromal period, complications, and measles were observed. The severity of the condition has no effect.
8.7. Investigations were carried out on six groups of children’s institutions that had a measles epidemic and were prevented with comfrey roots. There were 499 persons (6 months to 6 years old) who had not had measles, 310 of them were taking lithospermum root fluid in these contacts, 61 people who injected placenta globulin, and 63 people who injected adult blood. The other 65 people did not receive any preventive protection measures. The resulting total of 488 cases, accounting for 97%. All of the 310 people taking comfrey root except one of the 51/2 months and one 6-month baby were all ill. The incubation period did not prolong and the condition did not decrease. There was no significant difference from the non-prevention group. There was no significant difference in the number of pneumonia- and bronchitis-associated patients who received contact with the root solution of comfrey. Sooner or later (after contact with the patient), geranium root solution does not have a significant relationship with the severity of the disease, and even if preventive medications are started before the first contact with the patient, it will not prevent the disease or reduce the disease.
9. 100% Lithospermum root decoction and compound Lithospermum root decoction (3 parts of Lithospermum root, 2 parts of Yinhua, and 1 part of licorice) were divided into 3 groups according to different doses. The first group used 0.4 g per kg body weight, 0.8 g per kg body weight in the second group, the third group was the compound decoction group, and the amount of the Lithospermum root was 0.8 g per kg body weight; one dose per day, divided into 3 times Clothing, and even served on the 3rd. A total of 359 persons (85% of the patients aged 5 years or older) were observed. Among them, 152 were in the preventive group, 30 were in contact with measles patients, and 26 were found to have onset; 207 in the control group and 48 in contact with measles patients. , Incidence 47. Of the 26 children who developed the disease, 19 were taking orally roots on the 4th day after exposure, indicating that even if the roots were used at the early stage of incubation, it did not prevent measles. The differences in the incidence of the three groups of different dosage forms and doses are not significant, and they do not show the effect of dose and dosage form on the incidence. After the application of Lithospermum root as a preventive agent, the course of the disease did not significantly shorten, but there were also cases of concurrent pneumonia.
Dosage
Oral: Decoction, 3-9g: or into the powder. For external use: Appropriate amount, cream or oil coating.
Source: "Chinese Materia Medica"
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