The pharmacological effects of reed rhizome
Pharmacological effects
Skeletal muscle has inhibitory effect
It can inhibit the contractile response caused by electrical stimulation of frog neuromuscular specimens and oxygen uptake and anaerobic glycolysis of rat diaphragm muscles, and can inhibit the reaction of actin-adenosine triphosphatase system, as well as weak central inhibition The effect showed a sedative effect on both rats and mice, and could be antagonistic to caffeine. Rabbits on EEG, amplitude increase occurs, reduce the frequency, showed inhibition on the function of the central nervous system. In the rat tail electrical stimulation test, there is analgesic effect, strength and aminopyrine similar. With antipyretic activity, antipyretic effects of TTG (Pseudomonas fluorescens purified complex polysaccharides) fever are better, and no effect on the fever caused by dinitrophenol. There is a transient inhibitory effect on polysynaptic reflex (cat femoral nerve - gastrocnemius muscle specimens). Intravenous injection can cause a short-term decrease in blood pressure in rabbits. Subcutaneous injections can cause a slight decrease in blood glucose, inhibiting isolated heart and isolated rabbit intestine, and have no significant effect on rabbit ear veins. Its toxicity is very low, mice oral 0.5g/(kg.d), lmo did not cause abnormal changes.
Relaxation of isolated guinea pig intestine
At a concentration of 2 x 10 (-5), the isolated rabbit small bowel contraction was significantly inhibited. Infusion of 4 mg into the rabbit's small intestine will slow the contraction of peristalsis. Daily oral administration of 2 mg to rats resulted in a significant increase in thyroid hormone in the blood. With mild anti-oxidation, it can prevent the oxidation of adrenaline. Mild estrogen-like effects. There is still an anti-cancer effect. The T/C of 6 and 12.5 mg of P388 in mice was 133 and 174%.
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